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This is the story of the author's unique scientific journey with one of the most remarkable men of 20th century science. The journey begins in Sri Lanka, the author's native country, with his childhood acquaintance with Fred Hoyle's writings. The action then moves to Cambridge, where the famous Hoyle - Wickramasinghe collaborations begin. A research programme which was started in 1962 on the carbonaceous nature of interstellar dust leads, over the next two decades, to developments that are continued in both Cambridge and Cardiff. These developments prompt Hoyle and the author to postulate the organic theory of cosmic dust (which is now generally accepted), and then to challenge one of the most cherished paradigms of contemporary science - the theory that life originated on Earth in a warm primordial soup. Two new chapters plus revisions to the other chapters bring the book up to date and thus make it more relevant, just as recent findings mesh with many of the ideas that had their origin in the first edition. Ongoing research relating to life outside the Earth, the search for extrasolar planets as well as panspermia connect with this earlier work, so that tracing links become easier. A Journey with Fred Hoyle is an intriguing book that delineates the progress of a collaboration spanning 40 years, through a sequence of personal reflections, anecdotes and reminiscences.