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Many newly proposed drugs suffer from poor water solubility, thus presenting major hurdles in the design of suitable formulations for administration to patients. This work addresses the latest techniques and materials to overcome these hurdles, providing a thorough review of current formulation strategies for a wide range of hydrophobic drugs. With a focus on critical formulation features and clinical studies, the book covers instrumentation, operation principles, applications, scale-up considerations, regulatory issues, and more. An essential guide for researchers in drug delivery, polymers, and biomaterials.