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Endocrinology is a complex specialty that spans a wide range of diseases, disorders, and conditions. The field is now moving toward an increasingly personalized approach to patient management, with a greater focus on mechanisms of disease and biomarkers. Written by internationally renowned specialists, the second edition of Endocrinology in Clinical Practice provides a cutting-edge, problem-orientated approach to the management of clinical problems in endocrinology. Highlights of the new edition include: * An overview of neuroendocrine disease * Strides made by the identification of aryl hydrocarbon receptor-interacting protein mutations in patients with familial isolated pituitary adenomas * The diverse roles of IGF-I * Changes in diagnostic imaging and the increasing use of positron emission tomography * The rapidly increasing incidence of neuroendocrine tumors and their management * Hereditary primary hyperparathyroidism and multiple endocrine neoplasia * Mechanistic and genomic advances related to disorders of calcium regulation and infertility * The endocrinology of aging * Protocols for pituitary function testing With complete updates to existing chapters, the second edition also presents new research data, diagnostic techniques, treatment options, and safety concerns related to existing therapies. This edition offers current guidance and scientifically focused information relevant to a range of clinical problems, making it an essential reference for practicing endocrinologists and specialist clinicians.