Six women are found dead in a hotel room - five are them are students, still in their teens. Tied up and tortured, these are signature killings recognised by the NYPD for the three bloody initials carved into each victim's forehead: D.O.A. Ex-cop Frank Quinn has faced this madman before and both men bear the scars from their last encounter. Killer and cop, hunter and prey, find themselves in a deadly game of matched wits where only one can prevail. It's not just about who will be killed, but who will survive.