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In this new edition of Fundamentals of Enzyme Kinetics all of the text has been thoroughly revised to explain concepts even more clearly, some of the material is reorganized into a more logical sequence, and there are many additions throughout the book. In particular, the important topic of irreversible inhibition is now covered in more detail than it was in previous editions, and there is a fuller discussion of methods for studying fast reactions. A novel feature is the inclusion of brief biographical sketches of ten of the scientists who developed our understanding and knowledge of enzyme catalysis. There are numerous new bibliographical references to take account of developments over recent years. There is no pretence of an encyclopaedic approach, but instead the emphasis is on the principles of enzyme kinetics, and especially on explaining these principles as simply and accurately as possible, so that readers will be well equipped to take the subject as far as they need.