Molecular Oncology (BOK)

Edward P Gelmann

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The genomic era has allowed enormous strides in our understanding of the molecular changes that underlie malignant transformation. Mutations have been discovered that are critical drivers of large cross-sections of human cancers. These discoveries have allowed us to find drugs that target these drivers and make important strides in treatment. Genomics and high-throughput technologies have illuminated the complexity of cancer and the facility with which cancers adapt during their natural history. The field is evolving rapidly with new discoveries and new drugs reported monthly. This book is a timely foundation for understanding in context the origins of molecular oncology and its future directions. The content reviews available technologies for the analysis of cancer tissues and genes; summaries of key oncogenic pathways from a molecular perspective; the technologies, pathways and targeted therapies of a wide range of human malignancies; and new pharmacologic therapies that have a common mechanistic target.

Produktfakta

Språk Engelsk Engelsk Innbinding Innbundet
Utgitt 2013 Forfatter Edward P Gelmann
Forlag
CAMBRIDGE UNIVERSITY PRESS
ISBN 9780521876629
Antall sider 984 Dimensjoner 22,4cm x 27,7cm x 4,4cm
Vekt 2962 gram Leverandør Bertram Trading Ltd
Andre medvirkende Charles L. Sawyers, Edward P. Gelman, Frank J. Rauscher