A practical manual aimed at graduate students, junior researchers, nervous professionals, or clinicians who are preparing to present talks at meetings and academic conferences. This is an important career skill for anyone in the sciences, and the book features step-by-step instruction for creating clear and compelling presentations - from structuring a talk and developing effective Powerpoint slides, through delivery before an audience. Includes color examples of slides and posters from actual presentations, and field-tested methods for success behind the podium. Also contains tips on answering questions and strategies for handling media and job interviews. The authors are professional public speakers who teach presentation skills to scientists and medical researchers at the National Institutes of Health and in the private sector.