Systems Biomedicine: Concepts and Perspectives (BOK)

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Systems biology is a critical emerging field that seeks to define the interactions of all biological components by examining underlying biochemical and genetic processes. It is a discipline that quantifies and annotates the complexity of biological systems in order to construct algorithmic models to predict outcomes from component input. Applications in medicine are revolutionizing our understanding of biological processes and systems. "Systems Biomedicine" is organized around foundations, computational modelling, network biology, and integrative biology, with the extension of examples from human biology and pharmacology, to focus on the applications of systems approaches to medical problems. There is an integrative approach to the underlying genomic, proteomic, and computational biology principles that provides researchers with guidance in the use of qualitative systems and hypothesis generators. To reflect the highly interdisciplinary nature of the field, careful detail has been extended to ensure explanations of complex mathematical and biological principles are clear with minimum technical jargon. This title is organized to reflect the important distinguishing characteristics of systems strategies in experimental biology and medicine. It provides precise and comprehensive measurement tools for constructing a model of the system and tools for defining complexity as an experimental dependent variable. It includes a thorough discussion of the applications of quantitative principles to biomedical problems.


Språk Engelsk Engelsk Innbinding Heftet
Utgitt 2009 Forlag
ISBN 9780123725509 Antall sider 448
Dimensjoner 15,2cm x 22,9cm x 3,3cm Vekt 975 gram
Leverandør Bertram Trading Ltd Andre medvirkende Douglas A. Lauffenburger, Edison T. Liu
Emner og form Physiology, Biomedical engineering, Medical genetics