The Human Pain System: Experimental and Clinical Perspectives (BOK)

Frederick A. Lenz, Edward G. Jones, Kenneth L Casey, William Darrell Willis

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Pain is a subject of significant scientific and clinical interest. This has resulted both from realistic rodent models, and the publication of imaging, psychological and pharmacological studies in humans. Investigators studying rodents refer to anatomical and physiological studies in non-human primates to make their results relevant to humans. Psychophysical and pharmacological studies in humans are interpreted in terms of anatomical and physiological studies in animals; primarily evidence from rodents and cats. There are significant differences in pain mechanisms between these species and primates. Over 20 years of imaging studies have demonstrated the activation of human cortical and subcortical structures in response to painful stimuli. Interpretation of these results relies upon an understanding of the anatomy and physiology of these structures in primates. Jones, Lenz, Casey and Willis review the anatomy and physiology of nociception in monkeys and humans, and provide a firm basis for interpreting studies in humans.

Produktfakta

Språk Engelsk Engelsk Innbinding Innbundet
Utgitt 2010 Forfatter Edward G. Jones, Frederick A. Lenz, Kenneth L Casey, William Darrell Willis
Forlag
CAMBRIDGE UNIVERSITY PRESS
ISBN 9780521114523
Antall sider 648 Dimensjoner 17,4cm x 24,7cm x 3,5cm
Vekt 1410 gram Leverandør Bertram Trading Ltd
Emner og form Neurology & clinical neurophysiology